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Ibruxen (Čáđóňčíčá 140ěă) - Čáđóęńĺí ( Ibrutinib) - Ŕíŕëîă Čěáđóâčęŕ/Imbruvika

Ibruxen (Čáđóňčíčá 140ěă) - Čáđóęńĺí ( Ibrutinib) – ŕíŕëîă Čěáđóâčęŕ ďđĺäńňŕâë˙ĺň ńîáîé ëĺęŕđńňâĺííűé ďđĺďŕđŕň, äĺéńňâóţůčé íŕ îńíîâĺ íčçęîěîëĺęóë˙đíîăî číăčáčňîđŕ ňčđîçčíčíŕçű Áđóňîíŕ.
Ôîđěŕ âűďóńęŕ
Âűďóńę ëĺęŕđńňâŕ îńóůĺńňâë˙ĺňń˙ â âčäĺ ęŕďńóë, îńíîâíűě âĺůĺńňâîě ęîňîđűő ˙âë˙ĺňń˙ čáđóňčíčá.
Äĺéńňâčĺ ďđĺďŕđŕňŕ
Đĺęîěĺíäóĺňń˙ ďđčíčěŕňü ďđĺďŕđŕň çŕ íĺńęîëüęî ÷ŕńîâ ëčáî äî ĺäű, ëčáî ďîńëĺ. Ďîďŕäŕ˙ â îđăŕíčçě, ëĺęŕđńňâî ńđŕçó ćĺ ŕáńîđáčđóĺňń˙. Äĺéńňâčĺ ďđĺďŕđŕňŕ íŕďđŕâëĺíî íŕ áîđüáó ń đŕęîâűěč ęëĺňęŕěč: îí îńňŕíŕâëčâŕĺň ďđîöĺńń čő đîńňŕ, ňĺě ńŕěűě ďđčâîä˙ ę óěĺíüřĺíčţ îďóőîëč. Ĺńëč âű őîňčňĺ Ibruxen (Čáđóňčíčá 140ěă) - Čáđóęńĺí ( Ibrutinib ) – ŕíŕëîă Čěáđóâčęŕ ęóďčňü íĺäîđîăî, ňîăäŕ îôîđěë˙éňĺ çŕęŕç íŕ íŕřĺě ńŕéňĺ.
Ďîęŕçŕíč˙ ę ďđčěĺíĺíčţ
Ďđčĺě ëĺęŕđńňâĺííîăî ńđĺäńňâŕ îńóůĺńňâë˙ĺňń˙ âçđîńëűěč, čěĺţůčěč ńëĺäóţůčĺ çŕáîëĺâŕíč˙: • Ěŕíňčéíîęëĺňî÷íŕ˙ ëčěôîěŕ; • Ëčěôîöčňŕđíűé ëĺéęîç; • Ěŕęđîăëîáóëčíĺěč˙ Âŕëüäĺíńňđĺěŕ.  îńíîâíîě, ëĺ÷ĺíčĺ äŕííűě ďđĺďŕđŕňîě îńóůĺńňâë˙ĺňń˙ â ňîě ńëó÷ŕĺ, ĺńëč ďŕöčĺíňű íĺ ěîăóň ďđîéňč ęóđń őčěčîňĺđŕďčč čëč čěěóííîňĺđŕďčč. Ďđî Ibruxen (Čáđóňčíčá 140ěă) - Čáđóęńĺí ( Ibrutinib ) – ŕíŕëîă Čěáđóâčęŕ îňçűâű ďî áîëüřĺé ÷ŕńňč ďîëîćčňĺëüíűĺ.
Ďîáî÷íîĺ äĺéńňâčĺ
 ęŕ÷ĺńňâĺ ďîáî÷íűő ýôôĺęňîâ ěîćíî îňěĺňčňü: • íŕđóřĺíč˙ đŕáîňîńďîńîáíîńňč íĺđâíîé ńčńňĺěű; • íŕđóřĺíč˙ đŕáîňîńďîńîáíîńňč ćĺëóäî÷íî-ęčřĺ÷íîăî ňđŕęňŕ; • íŕđóřĺíč˙ çđĺíč˙; • ŕëëĺđăč÷ĺńęčĺ đĺŕęöčč. Ňŕęćĺ ěîćĺň ďđî˙âčňüń˙ ńëŕáîńňü čëč îňĺę. Ĺńëč ďîáî÷íűĺ ýôôĺęňű čěĺţň ńëŕáîĺ äĺéńňâčĺ, ňî ďđčĺě ďđĺďŕđŕňŕ ďđîäîëćŕĺňń˙ â îáű÷íîě đĺćčěĺ.  ďđîňčâíîě ńëó÷ŕĺ ďđč óőóäřĺíčč ńîńňî˙íč˙ ďŕöčĺíňŕ ďđčĺě ďđĺďŕđŕňŕ ďđĺęđŕůŕĺňń˙ č íŕçíŕ÷ŕĺňń˙ ęîíńóëüňŕöč˙ ó ëĺ÷ŕůĺăî âđŕ÷ŕ. Óçíŕňü, ęŕęŕ˙ ńĺăîäí˙ íŕ Ibruxen (Čáđóňčíčá 140ěă) - Čáđóęńĺí ( Ibrutinib ) – ŕíŕëîă Čěáđóâčęŕ ńňîčěîńňü ěîćíî, ďîçâîíčâ â íŕřó ŕďňĺęó.
Ďđîňčâîďîęŕçŕíč˙
Čáđóňčíčá íĺ đĺęîěĺíäóĺňń˙ ďđčíčěŕňü: • áĺđĺěĺííűě č ęîđě˙ůčě ćĺíůčíŕě; • äĺň˙ě â âîçđŕńňĺ äî 18 ëĺň; • áîëüíűě, čěĺţůčě ăčďĺđ÷óâńňâčňĺëüíîńňü ę ęŕęîěó-ëčáî čç ęîěďîíĺíňîâ ďđĺďŕđŕňŕ; • ďŕöčĺíňŕě, ó ęîňîđűő čěĺţňń˙ ďđîáëĺěű ń ďĺ÷ĺíüţ č ďî÷ęŕěč. Ňŕęćĺ çŕďđĺůĺíî ďđčěĺíĺíčĺ ďđĺďŕđŕňŕ â ńëó÷ŕ˙ő, ĺńëč âĺäĺňń˙ ďŕđŕëëĺëüíűé ęóđń ëĺ÷ĺíč˙ ěîůíűő ďđĺďŕđŕňîâ. Ńđĺäč ňĺő, ęňî áűë âűíóćäĺí ďđîéňč ęóđń ëĺ÷ĺíč˙ äŕííűě ďđĺďŕđŕňîě, áűëî îňěĺ÷ĺíî ň˙ćĺëîĺ âëč˙íčĺ Čáđóňčíčáŕ íŕ îđăŕíčçě. Ďî ěíĺíčţ íĺęîňîđűő, â ňĺ÷ĺíčĺ ďđčĺěŕ ëĺęŕđńňâŕ ďđî˙âčëčńü ěíîăčĺ ďîáî÷íűĺ ýôôĺęňű, îńîáĺííî ÷ŕńňî – ęđîâîňĺ÷ĺíč˙ č íŕđóřĺíč˙ äűőŕňĺëüíűő ôóíęöčé. Âńĺ ýňî ďđčâîäčëî ę ňîěó, ÷ňî íóćíî áűëî ďîńňî˙ííî ęîđđĺęňčđîâŕňü äîçó ëĺęŕđńňâŕ.  ëţáîě ńëó÷ŕĺ îňďóńę ďđĺďŕđŕňŕ îńóůĺńňâë˙ĺňń˙ ďî đĺöĺďňó âđŕ÷ŕ. Č äë˙ ňîăî, ÷ňîáű áűë íŕçíŕ÷ĺí čěĺííî
Ibruxen (Čáđóňčíčá 140ěă) - Čáđóęńĺí ( Ibrutinib ) – ŕíŕëîă Čěáđóâčęŕ öĺíŕ ęîňîđîăî áîëĺĺ äîńňóďíŕ, íĺîáőîäčěî ďđîéňč ńďĺöčŕëüíîĺ îáńëĺäîâŕíčĺ č ńäŕňü ňđĺáóĺěűĺ ŕíŕëčçű. Ëĺ÷ŕůčé âđŕ÷ ńäĺëŕĺň âűâîä î âčäĺ çŕáîëĺâŕíč˙ č âűďčřĺň ńîîňâĺňńňâóţůčé đĺöĺďň


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